Anti-TPO Antibody Blood Test
Book the Anti-TPO test by Thyrocare at ₹799 with free home or office sample collection. The test is used in the investigation of Hashimoto’s thyroiditis and other autoimmune thyroid conditions.
About the Anti-TPO Test
Thyroid peroxidase is an enzyme used by the thyroid gland to make thyroid hormones. In autoimmune thyroid disease, the immune system can form antibodies against this enzyme. The Anti-TPO blood test measures these antibodies.
Anti-TPO antibodies are commonly found in Hashimoto’s thyroiditis. They can also be present in Graves’ disease and in some persons whose TSH and thyroid hormone results are still within range.
When is the test advised?
Doctors advise Anti-TPO testing when TSH is raised, thyroid hormone results are abnormal, the thyroid gland is enlarged or inflamed, or symptoms such as fatigue, cold intolerance, constipation, dry skin, and unexplained weight gain are present.
Anti-TPO Normal Range and Result Interpretation
| Anti-TPO value | Report result |
|---|---|
| Below 9 IU/mL | Negative |
| 9 IU/mL or above | Positive |
Reference ranges can vary between laboratories. The values shown here follow the reference range used by Thyrocare for the CLIA method.
Positive Anti-TPO with raised TSH
This pattern can occur in Hashimoto’s thyroiditis when thyroid hormone production has fallen. Free T4 helps determine the current thyroid hormone status.
Positive Anti-TPO with normal TSH
Thyroid autoimmunity can be present before thyroid function becomes abnormal. The doctor can advise follow-up TSH testing.
Positive Anti-TPO with hyperthyroidism
Anti-TPO antibodies can also be found in Graves’ disease. TRAb or TSI testing is more directly related to Graves’ disease.
Anti-TPO and Other Thyroid Tests
| Test | What it checks |
|---|---|
| Anti-TPO | Antibodies against thyroid peroxidase, commonly associated with Hashimoto’s thyroiditis |
| TSH and Free T4 | Current thyroid function and whether the results indicate hypothyroidism or hyperthyroidism |
| Anti-Thyroglobulin | Antibodies against thyroglobulin, another thyroid protein |
| TRAb or TSI | Antibodies acting on the TSH receptor, mainly tested for Graves’ disease |
Book the Thyrocare Anti-TPO Test
Share the beneficiary’s name, age, gender, mobile number, email address, complete collection address with PIN code, and preferred collection time.
- Free home or office sample collection
- Payment during sample collection
- Report delivery through WhatsApp and email
Anti-TPO Sample Report
View the Thyrocare sample report for anti-thyroid peroxidase antibodies (Anti-TPO) or the Anti-Microsomal Antibody (AMA) blood test.
View Sample Report PDFRelated Thyroid Tests and Profiles
Medical references: American Thyroid Association , MedlinePlus , and NIDDK .
FAQs on the Anti-TPO Test
Does a positive Anti-TPO result confirm Hashimoto’s thyroiditis?
No. Anti-TPO antibodies are commonly found in Hashimoto’s thyroiditis, but the doctor also considers TSH, Free T4, symptoms, examination, and medical history.
Is a very high Anti-TPO level dangerous?
There is no universal Anti-TPO value that independently shows danger or disease severity. TSH, Free T4, symptoms, and the medical condition are more important for treatment decisions.
Does the Anti-TPO test need to be repeated?
Repeated Anti-TPO testing is not required in many established Hashimoto’s thyroiditis cases. Follow-up commonly depends more on TSH and thyroid hormone results.