
Thyroid Profile with Ultrasensitive TSH
Book Thyrocare’s Ultrasensitive Thyroid Function Test (TFT) profile across India. It includes Total T3, Total T4, and a 3rd-generation Ultrasensitive TSH marker to provide higher analytical sensitivity for thyroid screening.
This Thyrocare Thyroid Profile with Ultrasensitive TSH is available at an offer price of ₹420 for Total T3, Total T4, and US-TSH testing with home sample collection.
Book Now, Pay During the Sample Collection
Ultrasensitive Thyroid Profile: Quick Facts
| Also Known As | TFT, Ultrasensitive TFT, 3rd Gen Thyroid Profile, High Sensitivity Thyroid Panel, T3-T4-TSH Profile. |
| Discounted Price | ₹420 (Offer Price) |
| Sample Type | Blood (Serum) |
| Fasting | Not required |
| Testing Lab | Thyrocare (NABL Accredited) |
| Clinical Use | Baseline thyroid screening, monitoring hormone replacement therapy, and detecting subclinical thyroid disease. |
| Reporting Time | 12 to 24 hours after sample collection |
| Service Type | Free home sample collection (in 2,500+ PIN code areas in India). |
What Is the Thyroid Profile with Ultrasensitive TSH?
The Thyroid Profile with Ultrasensitive TSH is a first-line diagnostic blood test used to evaluate the physiological feedback loop of the thyroid gland. It measures Total Triiodothyronine (T3) and Total Thyroxine (T4) alongside a highly precise 3rd-generation TSH (Thyroid Stimulating Hormone) assay.
By utilizing advanced CLIA (Chemiluminescence Immunoassay) and CMIA (Chemiluminescent Microparticle Immunoassay) technology, this profile moves beyond basic screening. The ultrasensitive TSH marker provides superior analytical sensitivity, enabling clinicians to detect minute hormone fluctuations and identify subclinical (early-stage) thyroid dysfunction before clear clinical symptoms appear in some cases.
Basic TSH vs. Ultrasensitive TSH (3rd Gen)
Both assays measure the same hormone, but their analytical sensitivity—the lowest concentration they can reliably detect—differs significantly.
- Basic or older TSH assays: Older TSH assay generations have lower analytical sensitivity and are mainly useful for routine thyroid dysfunction assessment. They are less suitable when very low or suppressed TSH values need precise measurement.
- Ultrasensitive TSH (3rd Gen): Detects TSH concentrations as low as 0.01 mIU/L to 0.02 mIU/L. This higher analytical sensitivity makes it useful for thyroid hormone replacement follow-up and for assessing suppressed or very low TSH values in suspected subclinical hyperthyroidism.
When to Upgrade to Advanced Panels?
While this 3-parameter Ultrasensitive TFT is ideal for routine screening, certain clinical scenarios require broader testing parameters.
- Free + Total Profiles (5 Tests): If protein-binding abnormalities are suspected (e.g., during pregnancy, liver disease, or with oral contraceptive use), clinicians often upgrade to testing Free T3 and Free T4 alongside Total hormones for a biologically active hormone assessment.
- Autoimmune Profiles (8+ Tests): If underlying autoimmune conditions like Hashimoto’s Thyroiditis or Graves’ disease are suspected, comprehensive panels including Anti-TPO, Anti-TG, and TSH Receptor antibodies are highly recommended.
Tests in the Ultrasensitive Thyroid Profile
The Thyrocare Thyroid Profile tests for 3 specific parameters to assess the baseline loop between the pituitary and thyroid glands.
List of 3 Tests
- Total Triiodothyronine (Total T3)
- Total Thyroxine (Total T4)
- Ultrasensitive TSH (3rd Gen)
Clinical Significance of Thyroid Markers
Evaluating T3, T4, and US-TSH together allows physicians to accurately categorize the physiological state of the thyroid and identify primary, secondary, or subclinical thyroid disorders.
| Specific Marker | Common Clinical Association / Significance |
|---|---|
| Ultrasensitive TSH (US-TSH) | Produced by the pituitary gland. An elevated US-TSH indicates an underactive thyroid (hypothyroidism), as the pituitary signals the gland to produce more hormone. A suppressed US-TSH indicates an overactive thyroid (hyperthyroidism). The 3rd-gen assay detects mild subclinical hyperthyroidism reliably. |
| Total Thyroxine (Total T4) | The predominant hormone secreted directly by the thyroid gland. Low levels correlate with hypothyroidism, while high levels indicate hyperthyroidism. Total T4 measures both the bound (inactive) and free (active) hormone circulating in the bloodstream. |
| Total Triiodothyronine (Total T3) | Mostly converted from T4 in peripheral tissues (e.g., liver), T3 is the highly active metabolic hormone. It is primarily measured to diagnose the severity of hyperthyroidism or “T3 thyrotoxicosis,” a condition where only T3 is elevated while T4 remains normal. |

How the Ultrasensitive TFT is Performed
The profile requires a standard blood test. At Thyrocare, the analytical process is structured as follows:
- A trained technician collects approximately 3 mL of venous blood.
- Fasting is not required for this thyroid profile unless another test in the same sample requires fasting.
- The serum is separated by centrifuging the sample and transported via a temperature-controlled cold-chain logistics network.
- Testing is executed using automated immunoassay technology: CLIA for Total T3 and Total T4, and CMIA for Ultrasensitive TSH.
- Results are technically verified and released digitally within 12 to 24 hours of sample collection.
How to Book the Thyroid Profile
- Message +91 70701 77147 on WhatsApp.
- Specify the “Ultrasensitive Thyroid Profile” and share the beneficiary’s details (name, age, gender, complete address with PIN code, email ID, and preferred slot).
- Our support team will instantly match your PIN code with available phlebotomists and confirm the booking.
- A Thyrocare technician will visit your home for the blood draw.
- You will receive your digital reports securely via WhatsApp and email.
Thyroid Profile: Sample Report
Sample reports are provided for format understanding. Your actual results will display patient-specific values mapped against biological reference intervals.
FAQs on Thyroid Profile with Ultrasensitive TSH
Who should choose the Thyroid Profile with Ultrasensitive TSH?
Is Ultrasensitive TSH better than a normal TSH test?
Should I book Total T3 and Total T4 or Free T3 and Free T4?
Can thyroid medicines affect my thyroid test result?
Can biotin affect thyroid blood test results?
Is this thyroid profile enough for Hashimoto’s or Graves’ disease?
Why can TSH be abnormal when T3 and T4 are normal?
What should I do if my thyroid report is abnormal?
References: American Thyroid Association (ATA) • MedlinePlus (TSH Test)
Note: This information is for educational and transactional purposes only. Always consult your physician or endocrinologist to correlate the Thyroid Function Test results with your clinical symptoms and medical history.
Written by: Hema Mehta Sahoo
Medically reviewed by: Dr. M A Khan, MBBS, MD Pathology
Last updated: May 15, 2026