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Antinuclear Antibody Profile (ANA/ENA Panel) Blot Test

Diagnosis for autoimmune disorders

ENA and ANA Blot Profile by Thyrocare: Parameters, Price, and Panel Details

About the ANA Profile

Overview

An Antinuclear Antibody (ANA) Profile or Extractable Nuclear Antigens (ENA) panel has many other names. This advanced blood test profile looks for certain antibodies against some antigens found in the nucleus of a cell to detect and differentiate different autoimmune disorders. The main purpose of the tests is to diagnose autoimmunity associated with Rheumatoid Arthritis, Sjögren’s Syndrome, Systemic Lupus Erythematosus (SLE), Mixed Connective Tissue Disease (MCTD), and some similar conditions.

An ENA/ANA Blot test by Thyrocare is an accurate and reliable diagnosis for autoimmune disorders.

Parameters in An ENA Profile by Thyrocare

The ENA or ANA Profile includes the following 17 to 18 parameters:

  • DsDNA
  • Nucleosome
  • HIstone
  • SmD1
  • PCNa
  • P0 (RPP)
  • SS – A/Ro60
  • SS – A/Ro52
  • SS – B/La
  • CENBP
  • Scl70
  • U1 – SnRNP
  • AMA M2
  • Jo – 1
  • PM – Scl
  • Mi – 2
  • Ku
  • DFS – 70

ENA/ANA Profile Sample Report

Here is a sample report of a typical ENA/ANA Panel Test:

Sample Report - ENA Test, ANA Profile, Antinuclear Antibody Panel. ANA 17 Blot, ANA 17 Profile

ENA/ANA 17 Blot by Thyrocare – Downloadable Sample Report

Frequently Asked Questions (FAQs) – ENA/ANA 17 Profile Test

As the ANA test profile has many different names and there are many different blood tests with similar names, confusion may happen. Here are answers to a few frequently asked questions that can clear the confusion.

  1. What is an ANA profile?

    An Antinuclear Antibody (ANA) profile is an advanced blood test panel that aims to diagnose autoimmune disorders caused by antibodies that attack the nucleus of healthy cells. This is one of the powerful diagnostic tools to detect abnormal immune responses created by antinuclear antibodies. The panel covers a graphical representation of 18 extractable nuclear antigens to confirm or rule out an autoimmune disorder.

  2. Is an ENA Panel different from an ANA Profile test?

    No, those are not different. Both ANA and ENA profiles are just different names of the same test panel. Besides these two names, the same autoimmunity detection panel has many other names, such as ANA 17 Blot, Antinuclear Antibodies 17 Pro, Extractable Antinuclear Antibody Profile, etc.

  3. What is the difference between an ANA test and an ANA profile?

    An Antinuclear Antibody (ANA) test is a standard blood test to measure the presence of ANA total in a blood sample. But an Antinuclear Antibody (ANA) profile test refers to an advanced group of tests that can find different Extractable Nuclear Antigens (ENA). The ANA profile test is advised if an ANA test report is found positive.

  4. Are both the RIANA (ANA by IFA) test and the ANA profile the same?

    No, both are not the same. Although both the ANA by IFA (ANA Titer) test and the ANA/ENA profiles aim to detect autoimmunity, both have many differences. Importantly, while the ANA by IFA can detect the total antinuclear antibody, an ANA profile can find all extractable antinuclear antibodies with specifications.

  5. When is an ENA/ANA blood test panel suggested?

    Your doctor may suggest an ENA profile test if an Antinuclear Antibody test report comes positive.

  6. Which autoimmune disorders can be checked by an ANA or ENA test profile?

    An ANA panel test can help in checking Rheumatoid Arthritis (RA), Scleroderma (Systemic Sclerosis), Sjögren’s Syndrome, Dermatomyositis, Systemic Lupus Erythematosus (SLE), Mixed Connective Tissue Disease (MCTD), and a few other disorders.

  7. What should I do if an ENA/ANA profile report comes positive?

    If you find one or more antinuclear antibodies in your report, you should consult your doctor. Based on the report and other clinical histories, he/she will decide the further action.

  8. How much does an ANA profile test cost?

    Depending on the number of parameters, testing lab standard, location, and the platform, the ANA/ENA panel price may vary. In India, it’s between ₹3,499 and ₹7,999. Some labs may charge a higher price. In association with our lab partner, Thyrocare, we offer the ANA/ENA profile at ₹3,499.

Read more about the ANA test here.

Most Important Thing to Keep in Mind before Booking an ANA Test Profile

A name may create much confusion, and similarities in names may create more. There are many different tests, profiles, and panels around the name ‘Antinuclear Antibody (ANA)’ with slight variations or non-remarkable suffixes or prefixes. All those don’t mean any specific test. Furthermore, many other names refer to a single test. Around the test or profile name ‘ANA’, there is a jungle of confusion, and confusion can be a hindrance in getting the proper diagnosis.

How to get out of such confusion? Here are the answers:

  • Any test name simply abbreviated as ‘ANA’ or ‘ANF’ refers to a single ELISA-based blood test. The test price varies from ₹700 to ₹1,000 in India.
  • ANA Titer or RIANA, or ANA by IFA test names refer to an advanced ANA test by the Immunofluorescence method. This test cost a little more than an ANA ELISA test.
  • An ANA Profile/Panel or ENA refers to an ANA 17 Blot test with 17 or more extractable nuclear antigens. The test panel is also known as the ANA 17 Profile or the ENA Blot Test. This profile costs around five times more than a simple ANA ELISA test or an ANA IFA test.

Other Relevant Autoimmunity Blood Tests

Test/Profile NameNo. of ParametersOffer PriceMRPBooking Option
Antinuclear Antibody, ANA, ANA by ELISA01₹779₹1,000WhatsApp to Book Now
RIANA – ANA by IFA – ANA Titre (Immunofluorescence)01₹799₹1,100WhatsApp to Book Now
Rheumatoid Arthritis Factor, RA Factor, RF01₹649₹800WhatsApp to Book Now
Anti-CCP (ACCP)01₹1,699₹2,400WhatsApp to Book Now
NK Cell (CD16 + CD56) Analysis (Immune Function Profile)32₹2,099₹4,500WhatsApp to Book Now
CD3+CD4+CD807₹1,999₹4,000WhatsApp to Book Now
Immune Function Panel32₹2,099₹4,500WhatsApp to Book Now
HLA B27 (by Flowcytometry)01₹1,999₹2,600WhatsApp to Book Now
HLA B27 Real Time PCR, HLA-B27 PCR01₹2,199₹3,600WhatsApp to Book Now
ASO Titer Test01₹629₹789WhatsApp to Book Now
Basic Arthritis Profile72₹1,999₹4,000WhatsApp to Book Now
Advanced Arthritis Profile76₹3,199₹6,000WhatsApp to Book Now

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