H. pylori IgG, IgA, and IgM Antibody Tests
Book Thyrocare’s H. pylori antibody profiles across India. Using ELISA, these tests detect IgG, IgA, and IgM immune responses against Helicobacter pylori to support gastroenterological evaluations.
Book Securely via WhatsApp, Pay During Sample Collection
Helicobacter Pylori Blood Test: Quick Facts
| Also Known As | H. pylori Antibodies Test, Anti-H. pylori Serology, Helicobacter Pylori IgG/IgA/IgM Test. |
| Starting Price | ₹1,099 (Offer Price for IgG) |
| Sample Type | Blood (Serum) – 3 mL |
| Fasting | Not required |
| Testing Lab | Thyrocare (NABL Accredited) |
| Clinical Use | Detecting systemic immune responses to H. pylori, a bacterium strongly linked to chronic gastritis and peptic ulcer disease. |
| Reporting Time | 24 to 36 hours after sample collection |
| Service Type | Free home sample collection (in 2,500+ PIN code areas across India). |
H. pylori Test Options & Prices
Thyrocare offers three specific antibody profiling options. Please select the option that matches your doctor’s test request or prescribed profile.
| Test Profile Name | Markers Included | Offer Price | MRP |
|---|---|---|---|
| H. pylori IgG | IgG antibody (1 Parameter) | ₹1,099 | |
| H. pylori IgG + IgA | IgG and IgA antibodies (2 Parameters) | ₹1,999 | |
| H. pylori IgG + IgA + IgM | IgG, IgA, and IgM antibodies (3 Parameters) | ₹2,799 |
What Are H. pylori Antibodies?
Helicobacter pylori is a prevalent spiral-shaped bacterium that colonizes the human stomach lining. It is a primary cause of chronic active gastritis and peptic ulcer disease, and is recognized as a major risk factor for gastric cancer.
When you are exposed to this bacterium, your immune system defends the body by producing specific proteins called antibodies. An H. pylori serology (blood) test does not look for the bacteria itself; rather, it measures the concentration of these antibodies (IgG, IgA, and IgM) in your blood to determine if your immune system has mounted a defense against an H. pylori infection.
Clinical Significance of IgG, IgA, and IgM Markers
Depending on your symptoms and clinical history, gastroenterologists may order a single IgG marker or a combination of all three immunoglobulins to evaluate the timeline and nature of your immune response.
| Antibody Marker | Diagnostic Role / Clinical Association |
|---|---|
| H. pylori IgG | This is the most clinically requested marker. IgG antibodies appear a few weeks after the initial infection and remain detectable in the blood for months or even years. A positive IgG result confirms that you have been exposed to H. pylori at some point, but it cannot differentiate between an active infection and a past (cured) infection. |
| H. pylori IgA | IgA is the predominant antibody found in mucosal secretions (like the stomach lining). IgA is associated with mucosal immune response to H. pylori and is interpreted along with symptoms, clinical history, and other findings. It does not confirm active infection by itself. |
| H. pylori IgM | IgM is the first antibody produced during an acute, primary immune response. It is rarely elevated in adults (as most infections occur in childhood) but can be useful in identifying a very recent or early-stage acute primary infection. |
Important Clinical Limitation: Because IgG antibodies can remain elevated long after H. pylori has been successfully eradicated via antibiotics, this blood test is not recommended to confirm if a treatment was successful (eradication testing). Clinicians typically prefer urea breath tests or stool antigen tests for post-treatment confirmation.
Laboratory Methodology & Process
Thyrocare conducts this test using immunoassay technology. The standard testing protocol includes:
- A trained phlebotomist collects 3 mL of venous blood.
- No fasting is required. You can eat and drink normally before the sample collection.
- The serum is extracted and processed using the ELISA (Enzyme-Linked Immunosorbent Assay) method, which measures the optical density (OD) ratio of the antibodies.
- Strict internal quality control (QC) checks are performed.
- Digitally verified reports are released within 24 to 36 hours of sample collection.
How to Book Home Collection
- Send a direct message to +91 70701 77147 on WhatsApp.
- Specify the exact profile prescribed (e.g., “H. pylori IgG” or “H. pylori IgG + IgA”).
- Provide the patient’s full name, age, gender, delivery email, and exact address with the PIN code.
- Our support team will check Thyrocare’s network availability for your PIN code and confirm the available time slot.
- A technician will visit your location to collect the blood sample.
Sample Report: H. pylori Antibodies
Review the format preview below to understand how the ELISA OD ratio is reported against biological reference intervals. Note that specific values, interpretation flags, and clinical comments will vary based on individual results.
FAQs: H. pylori Blood Tests
What does the H. pylori IgG blood test measure?
Is fasting required for this test?
What sample is collected and how is it collected?
Do you provide home sample collection?
When will I receive the report?
Can this antibody test confirm an active infection?
References: Healthline (H. pylori Overview) • Mayo Clinic (H. pylori Symptoms) • Cleveland Clinic (H. pylori Infection)
Note: This information is strictly for educational and test booking purposes. H. pylori antibody tests cannot confirm if an infection is currently active or if eradication treatment was successful. Always consult a gastroenterologist or physician to correlate these results with your clinical symptoms and medical history.
Written by: Hema Mehta Sahoo
Medically reviewed by: Dr. M A Khan, MBBS, MD Pathology
Last updated: May 16, 2026